Avascular Necrosis (Knee)

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Avascular necrosis (AVN), also known as osteonecrosis, is a condition resulting from significant blood supply loss in a particular area of bone tissue. Most often AVN affects the knee, though it can occur in any bone in the body.


Loss of circulation in the affected joint or bone causes bone tissue to die and, in rare instances, can result in a collapse of the bone structure. AVN can also lead to advanced progression of osteoarthritis.

AVN can occur as the result of a trauma which cuts off blood supply, the use of systemic steroids or inflammatory diseases such as lupus or sickle cell anemia.

Symptoms of AVN usually begin with sudden knee pain, which can be triggered by routine activity. Other symptoms include swelling in the knee, limited range of motion and sensitivity to pressure or touch.

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